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See disease through biology.

We decode the biological signals driving disease using AI, starting with coronary artery disease.

  • Universitätsspital Basel
  • Maastricht UMC+
  • Herz- und Gefäßzentrum Bad Bevensen
  • Dedalus
Multi-well assay plate
The science

The biology is already in the blood

Coronary artery disease leaves measurable traces in routine clinical chemistry. Cardio Explorer® reads those biological signals and translates them into an individualised likelihood of obstructive disease.

  • Individualised, sex-specific pre-test probability from routine blood chemistry
  • No new tests or sampling: signals extracted from data already captured
  • Validated against invasive coronary angiography across European cohorts
Clinical evidence

More than a decade of peer-reviewed evidence

A continuous research program: from the foundational diagnostic algorithm to independent validation across Europe and a prospective implementation study now underway.

5
Clinical studiesFrom algorithm development through intended-use validation.
3
CountriesSwitzerland, Germany, and the Netherlands.
>4,500
PatientsAcross retrospective cohorts and ongoing prospective evaluation.
SHIFT

The future of coronary artery disease care

A normal ECG and troponin rule out an acute myocardial infarction—not obstructive coronary artery disease. As a result, many patients with clinically important CAD leave the hospital undiagnosed. Cardio Explorer® changes that.

Hidden disease
In a landmark chest pain cohort, approximately 1 in 10 patients initially cleared after routine assessment were subsequently found to have obstructive CAD.1View clinical evidence
Made visible
Cardio Explorer® analyzes routine clinical and laboratory data already collected during care—requiring no additional tests and no workflow changes—to identify patients whose obstructive CAD would otherwise remain undetected.Explore product
Better decisions
Patients identified by Cardio Explorer® can be referred for appropriate downstream testing or catheterization earlier, improving patient selection and increasing the diagnostic yield of the cath lab.View clinical evidence
Obstructive CAD No obstructive CAD
  1. 1.Hoffmann U, et al. Coronary CT angiography versus standard evaluation in acute chest pain (ROMICAT-II). N Engl J Med. 2012;367(4):299–308. doi:10.1056/NEJMoa1201161
Integrations

Built into the systems your team already uses

Cardio Explorer® runs natively inside Dedalus ORBIS, on routine data already captured — no new tests, no new documentation, no new workflow.

Using a different clinical information system? Contact our team.

Dedalus ORBIS
Your EMR
OUTCOMES

Outcomes that matter

Cardio Explorer® is designed to help identify patients with clinically significant coronary artery disease earlier and support more deliberate allocation of cardiovascular resources.

Identify

More actionable CAD identified

Surface patients with clinically significant coronary artery disease who may otherwise remain undiagnosed.

Prioritize

Higher-yield coronary pathways

Improve the proportion of patients progressing through advanced imaging and invasive evaluation who have actionable disease.

Optimize

Better use of scarce cardiovascular resources

Focus specialist time, imaging capacity, and cath-lab utilization where they can create the greatest clinical impact.

Voices from the field

Built with the teams who run cardiac care

We believe Cardio Explorer®, Exploris Health's innovative cardiac test, will significantly improve care for patients with suspected coronary artery disease.
Dr. med. Thomas Helms
Dr. med. Thomas Helms
Chairman of the Board, German Foundation for the Chronically Ill
Cardio Explorer® achieves a precision of over 95% in calculating individualized and sex-specific pre-test probability and enables significantly better patient steering than any other solution currently available on the market.
Prof. Bjoern Remppis
Prof. Bjoern Remppis
Interventional Cardiologist, Herz- und Gefäßzentrum Bad Bevensen
This is certainly an important step forward and has a big potential for the entire diagnostic process of coronary artery disease.
Prof. Hans-Peter Brunner-La Rocca
Prof. Hans-Peter Brunner-La Rocca
Vice Chairman, Department of Cardiology — Head, Heart Failure Clinic, Maastricht University Medical Centre
From data to diagnostic confidence. The Cardio Explorer® unlocks the full potential of available patient data to safely rule out coronary artery disease.
Michael Zellweger, MD
Michael Zellweger, MD
Professor of Cardiology — Head of Cardiac Imaging, Cardiology Department, University Hospital Basel, Switzerland
We believe Cardio Explorer®, Exploris Health's innovative cardiac test, will significantly improve care for patients with suspected coronary artery disease.
Dr. med. Thomas Helms
Dr. med. Thomas Helms
Chairman of the Board, German Foundation for the Chronically Ill
Cardio Explorer® achieves a precision of over 95% in calculating individualized and sex-specific pre-test probability and enables significantly better patient steering than any other solution currently available on the market.
Prof. Bjoern Remppis
Prof. Bjoern Remppis
Interventional Cardiologist, Herz- und Gefäßzentrum Bad Bevensen
This is certainly an important step forward and has a big potential for the entire diagnostic process of coronary artery disease.
Prof. Hans-Peter Brunner-La Rocca
Prof. Hans-Peter Brunner-La Rocca
Vice Chairman, Department of Cardiology — Head, Heart Failure Clinic, Maastricht University Medical Centre
From data to diagnostic confidence. The Cardio Explorer® unlocks the full potential of available patient data to safely rule out coronary artery disease.
Michael Zellweger, MD
Michael Zellweger, MD
Professor of Cardiology — Head of Cardiac Imaging, Cardiology Department, University Hospital Basel, Switzerland
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Bring biological insight into your coronary pathway

See how Cardio Explorer® fits into your existing workflow and where it can improve who reaches invasive evaluation.