More actionable CAD identified
Surface patients with clinically significant coronary artery disease who may otherwise remain undiagnosed.
See disease through biology.
We decode the biological signals driving disease using AI, starting with coronary artery disease.
ISO 13485
ISO 27001
- Universitätsspital Basel
- Maastricht UMC+
- Dedalus
The biology is already in the blood.
Coronary artery disease leaves measurable traces in routine clinical chemistry. Cardio Explorer® reads those signals and turns them into an individualised likelihood of obstructive disease.
No new test. Just the biology that is already there.
- 10+
years of peer-reviewed research
- 87.8%
AUC in pivotal validation
- 4,500+
patients in the published studies
A new way to understand coronary artery disease
Cardio Explorer® turns routine clinical and biomarker data into an individualized estimate of obstructive CAD, placing each patient on the disease spectrum before imaging or catheterisation.
Unlike conventional risk scores that rely on population correlations, Cardio Explorer® models the underlying biology of atherosclerosis to deliver a more personalised and robust assessment of disease likelihood.
Risk class
Very Low
CAD-CL
4%Recommendation
Defer further cardiac testing; manage any modifiable risk factors per preventive-care guidelines.
Learn more
05%15%50%85%100%
Very lowLowModerateHighVery high
Illustrative. Drag the marker to see how a clinical likelihood maps to its ESC-guideline recommendation. Not a diagnostic tool.
Instructions for UseMaking coronary artery disease visible earlier
A normal troponin and ECG rule out myocardial infarction. They do not rule out obstructive coronary artery disease. Cardio Explorer® estimates each patient's likelihood of obstructive CAD from routine clinical and laboratory data.
Hidden disease
Routine assessment can exclude an acute myocardial infarction while clinically important coronary artery disease remains undetected. In the ROMICAT II trial, around 1 in 8 chest pain patients with a normal initial troponin and ECG had significant coronary stenosis (≥50%) on CT angiography.1 (source 1)
Made visible
Cardio Explorer® combines routine clinical data and standard blood tests into an individual pre-test probability of obstructive CAD.
Earlier action
A low estimate supports deferring further testing. A high estimate supports referral for CT angiography or functional testing.
- Chest pain: 13.8% with obstructive CAD. Troponin-negative ED patients with chest pain. Source 1.
- Atrial fibrillation: 21.0% with obstructive CAD. Patients undergoing AF ablation work-up. Source 2.
- Heart failure: ≥35.8% with obstructive CAD. Patients admitted with heart failure. Source 3.
- Chest pain: troponin-negative ED patients (normal initial troponin and ECG): Ferencik et al., JACC Cardiovasc Imaging 2015 (ROMICAT II), n = 160, ≥50% stenosis on CCTA, doi:10.1016/j.jcmg.2015.06.016.
- Atrial fibrillation: patients undergoing AF ablation work-up: Herczeg et al., Coron Artery Dis 2023, n = 2,321, ≥50% stenosis on CCTA, doi:10.1097/MCA.0000000000001201.
- Heart failure: patients admitted with HFpEF: Rush et al., JAMA Cardiol 2021, n = 106; 38 of 106 enrolled (51% of those catheterised), doi:10.1001/jamacardio.2021.1825.
Built into the systems your team already uses
Cardio Explorer® runs natively inside Dedalus ORBIS, on routine data already captured — no new tests, no new documentation, no new workflow.
Using a different clinical information system? Contact our team.
+ Your EMR
Cardio Explorer®
Clinician
Automated risk report
Outcomes that matter
Cardio Explorer® is designed to help identify patients with clinically significant coronary artery disease earlier and support more deliberate allocation of cardiovascular resources.
Higher-yield coronary pathways
Improve the proportion of patients progressing through advanced imaging and invasive evaluation who have actionable disease.
Better use of scarce cardiovascular resources
Focus specialist time, imaging capacity, and cath-lab utilization where they can create the greatest clinical impact.
Built with the teams who run cardiac care
We believe Cardio Explorer®, Exploris Health's innovative cardiac test, will significantly improve care for patients with suspected coronary artery disease.
Dr. med. Thomas Helms
Chairman of the Board, German Foundation for the Chronically Ill
This is certainly an important step forward and has a big potential for the entire diagnostic process of coronary artery disease.
Prof. Hans-Peter Brunner-La Rocca
Vice Chairman, Department of Cardiology — Head, Heart Failure Clinic, Maastricht University Medical Centre
From data to diagnostic confidence. The Cardio Explorer® unlocks the full potential of available patient data to safely rule out coronary artery disease.
Michael Zellweger, MD
Professor of Cardiology — Head of Cardiac Imaging, Cardiology Department, University Hospital Basel, Switzerland
We believe Cardio Explorer®, Exploris Health's innovative cardiac test, will significantly improve care for patients with suspected coronary artery disease.
Dr. med. Thomas Helms
Chairman of the Board, German Foundation for the Chronically Ill
This is certainly an important step forward and has a big potential for the entire diagnostic process of coronary artery disease.
Prof. Hans-Peter Brunner-La Rocca
Vice Chairman, Department of Cardiology — Head, Heart Failure Clinic, Maastricht University Medical Centre
From data to diagnostic confidence. The Cardio Explorer® unlocks the full potential of available patient data to safely rule out coronary artery disease.
Michael Zellweger, MD
Professor of Cardiology — Head of Cardiac Imaging, Cardiology Department, University Hospital Basel, Switzerland
A platform you can trust
Built to the standards hospital teams expect.
Independently certified.
A CE-marked IVD under the EU IVDD, developed under an ISO 13485 quality management system.
Your data stays protected.
Patient data is protected through ISO 27001 certified information-security processes.
Built to medical standards.
Every release follows the IEC 62304 medical device software development lifecycle.
Latest news & research
Event
Prof. Hans-Peter Brunner-La Rocca Presents Cardio Explorer® at ESC Munich
Presented at the Digital Health Symposium at ESC Munich — how multi-marker AI can improve the assessment of obstructive coronary artery disease and patient selection for downstream testing.
Watch the video· 24 min
Event
Strategic growth project for the Cardio Explorer® with the GCC
Exploris Health announces a strategic growth initiative for the Cardio Explorer® in collaboration with the GCC.
Event
Exploris Health at the 9th Heidelberg Health Forum
Exploris Health participates in the 9th Heidelberg Health Forum to present its healthcare innovations.
Publication
New publication: AI-based diagnosis of coronary heart disease — the Cardio Explorer® in focus
New research demonstrates the Cardio Explorer®'s effectiveness in AI-driven coronary heart disease diagnosis.
Bring biological insight into your coronary pathway
See how Cardio Explorer® fits into your existing workflow and where it can improve who reaches invasive evaluation.